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Microdosing & Formulations Published by Dr. Elena Rostova (Ph.D. in Clinical Neurobiology & Somatosensory Systems) • 9 min read DOI: 10.1007/s00213-018-5049-7

Cognitive Flexibility and Divergent Thinking: Evaluating Microdose Psilocybin Protocols on Executive Function and Flow States

Executive Summary

Microdosing involves the ingestion of sub-hallucinogenic doses (typically 100mg to 300mg of raw mushroom equivalent, or 1-3 squares of Mystic Toad 3000mg artisan bars) on systematic schedules. Controlled psychometric evaluations reveal enhanced lateral problem-solving, reduced ruminative self-talk, and improvements on the Torrance Tests of Creative Thinking (TTCT).

1. Divergent vs. Convergent Problem-Solving in Modern Neuroscience

Convergent thinking seeks a single correct answer through strict deductive logic, whereas divergent thinking explores novel, unorthodox connections across distinct knowledge domains.

Sub-perceptual 5-HT2A stimulation allows distant semantic associations to cross cognitive thresholds, unlocking inventive solutions.

Primary Scientific Citations

  • Prochazkova, L., et al. (2018). Exploring the Effect of Microdosing Psychedelics on Creativity in an Open-Label Natural Setting. Psychopharmacology • DOI: 10.1007/s00213-018-5049-7
  • Polito, V., & Stevenson, R. J. (2019). A Systematic Study of Microdosing Psychedelics. PLOS ONE • DOI: 10.1371/journal.pone.0211023
Citation (APA 7th): Rostova, E. (2026). Cognitive flexibility and divergent thinking: Evaluating microdose psilocybin protocols on executive function and flow states. Mystic Toad Science Research Index, 1(24), 313-329.